Research Assistant Position at Columbia University

The Ho Laboratory is seeking a talented and enthusiastic Technician to join our team. We use in situ cryo electron tomography (cryoET) to explore how membrane protein complexes mediate host-pathogen interactions in the malaria parasite Plasmodium falciparum. Projects will be focused using cryoFIB milling and cryoET to directly visualize the host-pathogen interface in parasite-infected human red blood cells. Our lab is located in the Department of Microbiology & Immunology at Columbia University Irving Medical Center in New York City, New York. More information here: www.cmholab.org/research. If interested, please send a cover letter, CV, and contact information for three references to Dr. Ho at ch3516@cumc.columbia.edu.

We are looking for an innovative, resourceful and adventurous scientist who enjoys learning new things and being part of an open, collaborative team. The successful candidate will join a vibrant, collegial research community and enjoy access to state-of-the-art electron microscopy facilities at Columbia, including:

  • Multiple Titan Krios microscopes with a Gatan BioQuantum energy filter, Gatan K3 direct electron detector, and Volta phase plate

  • An Aquilos cryo-FIB/SEM microscope, Leica cryo-correlative fluorescence light microscope, Zeiss LSM800 cryo-confocal with AiryScan detector

  • A Glacios screening microscope with a Gatan K3 direct electron detector

  • An F20 screening microscope with a K2 Summit direct electron detector

Salary and benefits are competitive based on experience.

Qualifications

  • A B.S. or equivalent in materials science, biophysics, or biomedical engineering.

  • Previous experience in one of more of the following areas is preferred: SEM, nanofabrication using a FIB-SEM or cryoFIB-SEM, and/or cryoET.

  • Previous experience with Python, C++, and/or MATLAB is a plus.

  • Strong communication, interpersonal and organizational skills, and excellent attention to detail.